Wang Yicheng,Zhang Yiming,Shi Xiaohua,Yang Zhi,Wang Shaoliang,Fan Dongli.Preparation and evaluation of a new biomimetic material-silicone rubber coated by hydroxyapatite[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(04):324-327.
Wang Yicheng,Zhang Yiming,Shi Xiaohua,Yang Zhi,Wang Shaoliang,Fan Dongli.Preparation and evaluation of a new biomimetic material-silicone rubber coated by hydroxyapatite[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(04):324-327.DOI:
Preparation and evaluation of a new biomimetic material-silicone rubber coated by hydroxyapatite
Objective To prepare a new biomimetic material-silicone rubber coated by hydroxyapatite (HA/SR) and optimize the technique parameters
as well as to evaluate its topography and physicochemical properties. Methods Silicon rubber was coated by HA powder (HA-1
particle diameter 40 μm) and HA particles (HA-2
particle diameter 150 μm), which were named HA-1/SR and HA-2/SR. The mechanical properties were evaluated by an electronic universal material testing instrument. The Scanning electron microscopy (SEM)
Fourier transform infrared spectrometry (FTIR) and X-ray photoelectron spectroscopy (XPS)were used to analyze the material surface properties. Results Hydroxyapatite was uniformly coated on the surface of SR. Using SEM we found that HA and SR attached tightly. FTIR and XPS illustrated that the physically binding did not destroy the chemical constitution of HA and SR. Even the Shore hardness
tensile strength
and elongation at break of HA/SR were significantly decrease compared with SR (P<0.05)
HA/SR still can meet the clinical demand. Conclusion Although some physical properties are significantly changed
HA/SR can still meet clinical demands. In addition
HA/SR may be more suitable as a soft-tissue implant than SR and has the potential to be used in plastic surgery as HA has good biocompatibility.