Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia

陈立朝; 许民辉; 徐伦山; 邹咏文

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Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia

更新时间：2026-01-09

- Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia
- Journal of Army Medical University Vol. 34, Issue 2, Pages: 175-177(2012)
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  CLC： R651.1;R745.11;R977.6
- Published：2012
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陈立朝,许民辉,徐伦山,邹咏文.麦克氏囊甘油注射治疗原发性三叉神经痛的临床疗效分析[J].陆军军医大学学报(原第三军医大学学报),2012,34(02):175-177.

　Chen Lizhao,Xu Minhui,Xu Lunshan,Zou Yongwen.Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(02):175-177.
陈立朝,许民辉,徐伦山,邹咏文.麦克氏囊甘油注射治疗原发性三叉神经痛的临床疗效分析[J].陆军军医大学学报(原第三军医大学学报),2012,34(02):175-177. DOI：

　Chen Lizhao,Xu Minhui,Xu Lunshan,Zou Yongwen.Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(02):175-177. DOI：

摘要

目的分析经皮穿刺麦克氏囊注射甘油治疗原发性三叉神经痛的疗效及其相关因素。方法回顾性分析我科1983年12月至2010年6月采用经皮穿刺麦克氏囊注射甘油治疗三叉神经痛4 873例。对症状、药物是否有效、穿刺成功的测试方法及穿刺时有无脑脊液流出等因素与疗效的关系进行分析。结果近期治愈率为97.3％（4 741/4 873），3 851例(79.0％)获随访1～26年，复发653例，总复发率为17.0%（653/3 851），术后10年总有效率为83.1％，无严重并发症发生。提示症状、术前口服药物是否有效、穿刺成功的测试方法及穿刺时有无脑脊液流出等因素均与疗效有关。结论经皮穿刺麦克氏囊注射甘油治疗三叉神经痛安全、微创、有效。症状典型、术前口服药物有效、穿刺测试阳性及穿刺时有脑脊液流出的患者，其疗效好。

Abstract

Objective To analyze the curative effect and related factors of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia. Methods Clinical data of 4 873 patients with trigeminal neuralgia treated with percutaneous glycerol injection into Meckel’s cavityour in our department from December 1983 to June 2010 were collected and retrospectively analyzed. Relationship between curative effect and various factors

such as symptoms

effectiveness of drugs

test method of successful puncture and whether the cerebrospinal fluid outflow

etc. were anlyzed. Results The immediate success rate of the procedure was 97.3%. Follow-up was carried out in 3 157 patients for 1 to 26 years. The long-term success rate was 83%. Recurrence rate was 16.9%. No serious adverse effect was observed. The analysis showed that there was a significant relationship between the curative effect and factors such as symptoms

the effectiveness of drugs

test method of successful puncture

and whether the cerebrospinal fluid outflow. No severe complication was found during follow-up. Conclusion Percutaneous glycerol injection into Meckel’s cavity is a safe

minimally invasive

and effective method to treat trigeminal neuralgia. Patients with typical symptoms

the effectiveness of drugs before surgery

test method of successful puncture

and the presence of cerebrospinal fluid (CSF) outflow have good curative effect.

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