Chen Rui,Chen Gong,Chen Rongchang,Chen Xin.Correlation between exertional dyspnea and dynamic hyperinflation in patients with chronic obstructive pulmonary diseases[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(18):1977-1979.
Chen Rui,Chen Gong,Chen Rongchang,Chen Xin.Correlation between exertional dyspnea and dynamic hyperinflation in patients with chronic obstructive pulmonary diseases[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(18):1977-1979.DOI:
Correlation between exertional dyspnea and dynamic hyperinflation in patients with chronic obstructive pulmonary diseases
Objective To study the correlation between exertional dyspnea and dynamic hyperinflation in patients with chronic obstructive pulmonary diseases (COPD). Methods Routine lung ventilation function
diffusing function
lung volume and symptom-limited progressive cycle ergometer exercise were tested in 34 stable COPD patients and 10 healthy controls. Two-thirds of their symptom-limited peak work rate was used to conduct high-intensity CWRE test. Borg dyspnea score
TBFV curve and inspiratory capability (IC) were detected every 1 min at rest and exercise. Results The IC was significantly lower in COPD patients at peak exercise than at rest (1.56±0.29 L vs 2.07±0.38 L
t=-5.642,P0.01). The ΔBorg was negatively correlated with the ΔIC in COPD patients (r=-0.59
P0.01). The mean expiratory flow and time were significantly lower in COPD patients than in healthy controls at peak exercise time (P0.05). Conclusion Dynamic hyperinflation is one of the important factors for dyspnea in stable COPD patients during high-intensity CWRE exercise. The decreased mean expiratory flow and time may be the reason for dynamic hyperinflation in COPD patients during exercise.