Chen Ting,Guo Dajing,Zhao Jiannong,Fang Zheng.Primary application of whole-brain CT perfusion imaging in patients with transient ischemic attack[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(23):2512-2515.
Chen Ting,Guo Dajing,Zhao Jiannong,Fang Zheng.Primary application of whole-brain CT perfusion imaging in patients with transient ischemic attack[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(23):2512-2515.DOI:
Primary application of whole-brain CT perfusion imaging in patients with transient ischemic attack
Objective To explore the value of whole-brain CT perfusion (CTP) imaging in patients with transient ischemic attack (TIA). Methods Whole-brain CTP was performed in 40 patients with clinically diagnosed TIA. The parameter maps of time to peak (TTP)
mean transit time (MTT)
cerebral blood flow (CBF)
and cerebral blood volume (CBV) were analyzed. Dynamic CT angiography (4D-CTA) images were also obtained. Results Fifty-eight areas of abnormal perfusion changes corresponding to clinical symptoms were found in 36 of the 40 patients with CTP. Prolonged TTP and MTT
decreased CBF and increased or non-changed CBV were detected in the abnormal perfusion areas. The differences of TTP
MTT and CBF of the affected side compared with those of the contralateral side were significant (P0.05)
but the difference of CBV was not (P0.05). 4D-CTA showed responsible vascular stenosis or occlusion in varying degrees. In the 40 patients
vascular stenosis was found in 32 patients
occlusion in 2 patients and normal in 6 patients. Conclusion Overall assessment of TIA can be achieved by whole-brain CTP imaging
which has a great value for the diagnosis and evaluation of TIA.
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