Li Haijun,Xie Lin,He Xiangge,Yue Li,Wang Yuan.Relationship of disc damage likelihood scale nomogram and optical coherence tomogram for primary chronic angle-closure glaucoma: report of 73 eyes[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(11):1183-1186.
Li Haijun,Xie Lin,He Xiangge,Yue Li,Wang Yuan.Relationship of disc damage likelihood scale nomogram and optical coherence tomogram for primary chronic angle-closure glaucoma: report of 73 eyes[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(11):1183-1186.DOI:
Relationship of disc damage likelihood scale nomogram and optical coherence tomogram for primary chronic angle-closure glaucoma: report of 73 eyes
Objective To evaluate relationships between the results of disc damage likelihood scale (DDLS) and the parameters of optical coherence tomography (OCT) for primary chronic angle-closure glaucoma. Methods Thirty-eight primary chronic angle-closure glaucoma patients (73 eyes) who admited in our department from October 2009 to August 2010 were enrolled in this study. Their DDLS score was assessed with a 90-diopters (D) Volk len under slit lamp for disc diameter and narrowest rim width
and then the eyes were graded according to the results of DDLS nomography. Retina nerve fiber layer (RNFL) thickness at different quadrants and clock positions and other parameters was tested by Stratus OCT 3 000 with RNFL3.4 program. The relationships of clinical DDLS score with OCT parameters were analyzed by correlation coefficients analysis. Results There were 17 eyes (23.3%) with large-diameter disc
41 eyes (56.2%) with moderate-diameter disc
and 15 eyes (20.6%) with small-diameter disc. Significant correlations were found between the DDLS scores and the RNFL thicknesses at superior
inferior and temporal quadrants (r=-0.673
P=0.000 1; r=-0.605
P=0.000 1;r=-0.499 P=0.001 4). But no correlation was seen between the score with the thickness at nasal quadrant (r=-0.352
P=0.060 2). There were significant correlations between the score with the thicknesses at 11
7
6
10 and 12 o’clock positions (r=-0.673
P=0.000 1; r=-0.605
P=0.000 1; r=-0.531
P=0.000 6;r=-0.525
P=0.000 7;r=-0.520
P=0.000 8)
but not with those at 3
2 and 8 o’clock positions (r=-0.320,P=0.050 1;r=-0.320
P=0.051 0;r=-0.297,P=0.070 2). The thicknesses at Avg
Smax and Imax parameters were also correlated with the score (r=-0.582
P=0.000 1;r=-0.504
P=0.001 2;r=-0.478
P=0.002 4). Conclusion Clinical DDLS assessment on optic nerve damage has a correlation with OCT parameters on RNFL thickness. DDLS is a useful method to evaluate the optic neuropathy of primary chronic angle-closure glaucoma.