Melioidosis

caused by its pathogenic agent Burkholderia pseudomallei

is a new tropical disease epidemic to Hainan

Guangdong

Hong Kong

Taiwan of China and other regions around Nanhai sea

and is regarded as a diffusing amphixenosis. Because of ready accessibility

resistance to most common antibiotics

high rate of infectivity via aerosols and no effective vaccine

this bacteria has been classified as category B priority pathogens by the WHO. Hainan is an island of great military values as barrier of Nanhai

and has draw more economical attention due to its becoming more important in international tourist industry. Therefore

the research of melioidosis is urgent to the public health and the safety of our country. In order to control the infection of Burkholderia  pseudomallei

more work has to be done about the pathogen

such as

the interaction between this pathogen and human

its secretory system

potential vaccine

and so on. This review focused on progress in the research of Burkholderia  pseudomallei

attempting to appeal public attention on the research of melioidosis.