Objective   To explore the relationship between airway mucosal lesions and prognosis in children with mycoplasma pneumoniae pneumonia.    Methods   The clinical data of 93 children with identified mycoplasma pneumoniae pneumonia and undergoing bronchoscopy admitted to our hospital from July 2007 to July 2010 were retrospectively reviewed. According to the prognosis of the disease

the patients were divided into persisting mycoplasma pneumoniae pneumonia group (with the process ≥1 month) and the non-persisting mycoplasma pneumoniae pneumonia group (with the process 1 month). The relationship between the airway mucosal lesions and prognosis were analyzed.    Results   Among the 93 children

19 patients were persisting mycoplasma pneumoniae pneumonia and 74 patients were non-persisting mycoplasma pneumoniae pneumonia. The common mucosal lesions in both groups were bronchial mucosal follicle-like hyperplasia

roughness

hyperemia

edema

microtubule reductus and increasing mucus secretion. But airway inflammatory stenosis

and mucus plug blocking were more common in the persisting group than in non-persisting group (7/19 vs 7/74

15/19 vs 12/74; P0.05). However

the granulation proliferation

mucosal erosions and bronchial obliteration were existed only in the persisting group.    Conclusion   Severe airway mucosal lesions in acute stage may be the important factor causing the prolonged process of mycoplasma pneumonia pneumonia.