Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study

乙成成; 刘雯雯; 张颖秋; 王湘芸; 郭志军; 殷仁富

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Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study

更新时间：2026-01-09

- Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study
- Journal of Army Medical University Vol. 33, Issue 4, Pages: 408-410(2011)
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  CLC： R181.32;R589;R743.33
- Published：2011
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乙成成,刘雯雯,张颖秋,王湘芸,郭志军,殷仁富.代谢综合征与无症状脑梗死的相关性研究[J].陆军军医大学学报(原第三军医大学学报),2011,33(04):408-410.

　Yi Chengcheng,Liu Wenwen,Zhang Yingqiu,Wang Xiangyun,Guo Zhijun,Yin Renfu.Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(04):408-410.
乙成成,刘雯雯,张颖秋,王湘芸,郭志军,殷仁富.代谢综合征与无症状脑梗死的相关性研究[J].陆军军医大学学报(原第三军医大学学报),2011,33(04):408-410. DOI：

　Yi Chengcheng,Liu Wenwen,Zhang Yingqiu,Wang Xiangyun,Guo Zhijun,Yin Renfu.Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(04):408-410. DOI：

摘要

目的探讨代谢综合征(metabolic syndrome

MS)及其各组分与无症状脑梗死(silent cerebral infarction

SCI)的相关性。方法连续收集我科2006年5月至2010年6月健康体检患者959例[男性693例，女性266 例，年龄(49.8±9.1)岁]，根据修订后的中国人代谢综合征诊断标准，将所有患者分为代谢综合征组(443例)和非代谢综合征组(516例)。比较两组患者无症状脑梗死的患病率并采用单因素和多因素Logistic回归法分析代谢综合征及其各组分与无症状脑梗死的相关性。结果单因素统计分析发现代谢综合征组罹患无症状脑梗死的比例明显高于非代谢综合征组(41.1% vs 27.5%

P0.000 1)。多因素Logistic回归分析显示代谢综合征与无症状脑梗死发病明显相关（OR=1.73

95%CI:1.24～2.41

P=0.001 2），在代谢综合征各组分内高血压（OR=1.40

95%CI: 1.05～1.88

P=0.023 0）、糖尿病（OR=1.75

95%CI:1.23～2.48

P=0.001 9）也是无症状脑梗死的独立危险因素，而其他组分无统计学意义。结论代谢综合征与无症状脑梗死关系密切，代谢综合征是无症状脑梗死的独立危险因素。

Abstract

Objective To determine whether metabolic syndrome (MS) is correlated with silent cerebral infarction (SCI). Methods A cross-sectional study of 959 health-screening subjects (693 men and 266 women

at a mean age of 49.8±9.1) who underwent a physical examination in our department from May 2006 to March 2010 was carried out. These individuals were then divided into MS group and non-MS group according to the modified criterion established by the Chinese Medical Association of Diabetes. Prevalence of SCI

was evaluated by the results of MIR scanning. Two groups were compared and the correlation between MS and SCI were analyzed by univariate and multivariate logistic regression analysis. Results The prevalence of SCI was much higher in MS group than in non-MS group (41.1% vs 27.5%

P0.01). Univariate analyses revealed that significant correlation was found between MS and SCI (Chi square=19.6

P0.01). Multivariate logistic analyses revealed that MS was significantly associated with SCI (OR=1.73

95%CI: 1.24-2.41

P=0.001 2). The components model of MS showed a strong significance between hypertension (OR=1.40

95%CI: 1.05-1.88

P=0.023 0) and diabetes mellitus (OR=1.75

95%CI: 1.23-2.48

P=0.001 9) and the risk of SCI. Conclusion There is a close correlation between MS and SCI. MS is an independent risk factor of SCI.

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