Hong Yukun,Chi Luxiang,Song Zhiyuan,He Guoxiang,Shu Maoqin,Liu Jianping,Tong Shifei,Jin Tao,Zhong Li.Curative effect of endovascular therapy on Takayasu arteritis: report of 48 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(23):2541-2544.
Hong Yukun,Chi Luxiang,Song Zhiyuan,He Guoxiang,Shu Maoqin,Liu Jianping,Tong Shifei,Jin Tao,Zhong Li.Curative effect of endovascular therapy on Takayasu arteritis: report of 48 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(23):2541-2544.DOI:
Curative effect of endovascular therapy on Takayasu arteritis: report of 48 cases
Objective To observe the curative effect of endovascular therapy including percutaneous transluminal angioplasty (PTA) and PTA plus stenting on Takayasu arteritis (TA). Methods Forty-eight inpatients with TA (17 males and 31 females) at the age of 19 to 53 years (27.6±18.1 years)
who underwent endovascular therapy(PTA only or PTA plus stenting)in Department of Cardiology
Southwest Hospital
Third Military Medical University (Chongqing
China) from January 2002 to May 2009
were enrolled in this study. Treatment outcome and data including erythrocyte sedimentation rate
C-reactive protein
CTA
MRA
Doppler vascular ultrasound findings obtained during a follow-up period of 42.8 months were analyzed. Results A total of 180 lesions were detected in the 48 patients by angiography. Of the 101 lesions that underwent endovascular therapy
29 were found in subclavian artery and arteria innominata
28 in carotid
34 in renal artery
2 in pulmonary
and 8 in coronary artery
respectively. Good revascularization was achieved in all these lesions. No residual stenosis occurred in 76 lesions (75.2%) with only minimal residual stenosis observed in 25 patients (24.8%). Restenosis was observed in 3 lesions (12.0%
3/25) after treatment with PTA only and in 5 lesions (6.5%
5/76) after treatment with PTA plus stenting during the follow-up period of 3 to 6 months. No significant complication occurred in all recurrent stenoses after endovascular therapy. Conclusion Endovascular therapy including simple PTA or PTA plus stenting is a safe and effective treatment modality for chronic inactive TA.