Application of tumor-associated antigen p62 in immunodiagnosis of carcinoma: A Meta-analysis

李慎柯; 柴玉荣; 张春霞; 鲁照明; 王凯娟; 代丽萍; 张建营

您当前的位置：

首页 >

文章列表页 >

Application of tumor-associated antigen p62 in immunodiagnosis of carcinoma: A Meta-analysis

更新时间：2026-01-09

- Application of tumor-associated antigen p62 in immunodiagnosis of carcinoma: A Meta-analysis
- Journal of Army Medical University Vol. 33, Issue 3, Pages: 270-273(2011)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R195.1;R341;R730.4
- Published：2011
- 稿件说明：
移动端阅览
李慎柯,柴玉荣,张春霞,鲁照明,王凯娟,代丽萍,张建营.肿瘤相关抗原p62应用于肿瘤免疫诊断的Meta 分析[J].陆军军医大学学报(原第三军医大学学报),2011,33(03):270-273.

　Li Shenke,Chai Yurong,Zhang Chunxia,Lu Zhaoming,Wang Kaijuan,Dai Liping,Zhang Jianying.Application of tumor-associated antigen p62 in immunodiagnosis of carcinoma: A Meta-analysis[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(03):270-273.
李慎柯,柴玉荣,张春霞,鲁照明,王凯娟,代丽萍,张建营.肿瘤相关抗原p62应用于肿瘤免疫诊断的Meta 分析[J].陆军军医大学学报(原第三军医大学学报),2011,33(03):270-273. DOI：

　Li Shenke,Chai Yurong,Zhang Chunxia,Lu Zhaoming,Wang Kaijuan,Dai Liping,Zhang Jianying.Application of tumor-associated antigen p62 in immunodiagnosis of carcinoma: A Meta-analysis[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(03):270-273. DOI：

摘要

目的分析肿瘤相关抗原p62在免疫诊断中的作用和价值。方法采用Cochrane系统评价方法，通过计算机检索中国学术期刊全文数据库、万方数据库、维普咨询网、中国生物医学文献数据库和PubMed、Springer、Elsevier、EBSCO 外文数据库，并辅以手工检索，检索时间截止至2010年6月。获取p62用于肿瘤血清学免疫诊断的病例-对照研究共18篇文献，采用Cochrane协作网Review Manager 4.2.8软件进行Meta分析。结果以p62能否应用于肿瘤的免疫诊断为题，共纳入17项研究，包括6种不同的肿瘤类型，含1554例肿瘤患者病例和1461例正常人对照，目的均是检测p62自身抗体在肿瘤患者和正常对照中出现的例数。统计得出总的效应统计量比值比(odds ratio，OR)及其95％CI为10.74(7.25~15.90)，差异具有统计学意义(P0.01)。结论 Meta分析结果表明肿瘤患者血清中抗p62自身抗体的检测在免疫诊断中具有实际应用价值。

Abstract

Objective To analyze the role of tumor-associated antigen p62 in immunodiagnosis of cancer. Methods Eighteen papers on case-control studies were searched from CNKI Full-text Database

China Medical Academic Conference Database

Wanfang Database

VIP Information Database

PubMed

Springer

Elsevier

and EBSCO plus manual search of related journals in Library of Zhengzhou University (till June 2010). A Meta-analysis of the data was performed using the Cochrane review manager software 4.2.8 (RevMan 4.2.8). Results The eligible 17 studies on the immunodiagnosis of cancer involving 6 different cancers with p62 included 1 554 cancer patients and 1 461 normal controls . Meta-analysis showed that the total odds ratio (OR) and 95% confidence interval (95%CI) were 10.74 (7.25 to 15.90

P0.01). Conclusion Detection of anti-p62 in sera of tumor patients is of practical value in immunodiagnosis of carcinoma.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Development and validation of a prediction model for amputation risk in patients with diabetic foot ulcers based on systematic review and meta-analysis

Effect of Del Nido cardioplegia solution on myocardial protection in adult cardiac surgery under cardiopulmonary bypass: a Meta-analysis

Levels of alanine aminotransferase and aspartate aminotransferase in coronavirus disease 2019 patients: a meta-analysis

Diagnostic value of whole body 18F-FDG PET/CT imaging in metastatic cancer of unknown primary: a Meta-analysis

Risk factors of severe and critical coronavirus disease 2019: a meta-analysis

Related Author

HAN Weidong

FAN Yiming

CHEN Pan

HU Nan

HU Shiqi

XIONG Te

YIN Rui

徐旭

Related Institution

Department of Dermatology， First Affiliated Hospital， Army Medical University （Third Military Medical University）

⁰