Objective   To investigate the effect of laparoscopic or laparotomy radical resection of colorectal carcinoma on gut movement in patients.  Methods   Forty-two patients with colorectal carcinoma hospitalized in our department from June 2008 to June 2009 were equally divided into laparoscope group and laparotomy group. Their postoperative bowel tones recovery time

bowel releasing time

detaining time of gastric tube

food-taking time and defecation time were recorded. Concentration of paracetamol (PAC) 12 h prior to and 12

24 and 48 h after surgery was measured with high performance liquid chromatography (HPLC).  Results  Laparoscope group had shorter time in above-mentioned time periods than laparotomy group (P0.01)

and the peak concentration of PAC appeared in 2 h. Postoperative gut transmission function was significantly degressive in the 2 groups compared with it before operation (P0.01)

especially in laparotomy group. In 24 h after operation

the PAC concentration was 57.51±7.91 mg/L in laparoscope group and 28.32±6.37 mg/L in laparotomy group

with significant difference between them (P0.01)

but there was no difference in 48 h after operation.  Conclusion  The recovery period of gut movement is shorter in patients with radical resection of colorectal carcinoma by laparoscope

than by traditional laparotomy. Moreover

observing gut movement with PAC drug absorption is easy

safe and repeatable in clinical postoperative people.