Correlation between intervention of multiple risk factors and myocardial ischemia in patients with type 2 diabetes

赵婕; 张忠辉; 黄定德; 李前伟; 陈兵

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Correlation between intervention of multiple risk factors and myocardial ischemia in patients with type 2 diabetes

更新时间：2026-01-09

- Correlation between intervention of multiple risk factors and myocardial ischemia in patients with type 2 diabetes
- Journal of Army Medical University Vol. 32, Issue 9, Pages: 967-970(2010)
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  CLC： R181.32;R542.202;R587.1
- Published：2010
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赵婕,张忠辉,黄定德,李前伟,陈兵.2型糖尿病多因素干预与心肌缺血相关性分析[J].陆军军医大学学报(原第三军医大学学报),2010,32(09):967-970.

　Zhao Jie,Zhang Zhonghui,Huang Dingde,Li Qianwei,Chen Bing.Correlation between intervention of multiple risk factors and myocardial ischemia in patients with type 2 diabetes[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(09):967-970.
赵婕,张忠辉,黄定德,李前伟,陈兵.2型糖尿病多因素干预与心肌缺血相关性分析[J].陆军军医大学学报(原第三军医大学学报),2010,32(09):967-970. DOI：

　Zhao Jie,Zhang Zhonghui,Huang Dingde,Li Qianwei,Chen Bing.Correlation between intervention of multiple risk factors and myocardial ischemia in patients with type 2 diabetes[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(09):967-970. DOI：

摘要

目的观察新诊断2型糖尿病患者多因素干预与心肌缺血的关系。方法新诊断2型糖尿病患者120例经血糖、血脂、血压强化干预8年后，采用腺苷负荷下心肌核素显像(myocardial perfusion imaging，MPI)评估心肌缺血，统计分析多因素控制达标情况与MPI阳性率之间的关系。结果本组患者心肌缺血阳性率为25%，Logistic分析示有胸闷史(OR=49.963

95%CI=9.525～262.067

P=0.000)，高血压超过130/85 mmHg(OR=4.684

95%CI=1.064～20.239

P=0.032)，总胆固醇超过4.66 mmol/L(OR=7.297

95%CI=1.247～42.691

P=0.027)，糖化血红蛋白超过7%(OR=4.640，95%CI=1.064～20.239

P=0.041)4项因素均为发生糖尿病性心肌缺血的高危因素。结论 4项危险因素控制不良的2型糖尿病患者心肌缺血发生率高。全面、严格控制危险因素，尽可能提高治疗达标率才可能减少心肌缺血的发生。

Abstract

Objective To observe the correlation between intervention of multiple factors and myocardial ischemia in patients with newly diagnosed type 2 diabetes. Methods Myocardial ischemia in patients with newly diagnosed type 2 diabetes (duration≤1 year) was assessed 8 years after intensified intervention of their blood sugar

lipid and pressure using adenosine load myocardial nuclide perfusion image. Correlation between multiple factor analysis results using SPSS 13.0 and positive rate of adenosine load myocardial nuclide perfusion image was observed. Results The positive rate of myocardial ischemia in patients included in this study was 25%. Logistic analysis showed that history of chest distress (OR=49.963

95%CI=9.525 to 262.067

P=0.000)

blood pressure130/85 mmHg (OR=4.684

95%CI=1.064 to 20.239

P=0.032)

total cholesterol4.66 mmol/L (OR=7.297

95%CI=1.247 to 42.691

P=0.027) and mean glycosylated hemoglobin 7% (OR=4.640，95%CI=1.064 to 20.239

P=0.041) were the high risk factors for myocardial ischemia in patients with type 2 diabetes. Conclusion Poor control of the 4 factors is the high risk factor for myocardial ischemia in patients with type 2 diabetes. Overall and effective control of such risk factors can decrease the incidence of myocardial ischemia and improve its treatment.

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