Irradiated pigskin graft dressing and recombinant human epidermal growth factor gel application in treatment of small-area partial-thickness burn: report of 135 cases
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Irradiated pigskin graft dressing and recombinant human epidermal growth factor gel application in treatment of small-area partial-thickness burn: report of 135 cases
Journal of Army Medical UniversityVol. 32, Issue 1, Pages: 71-73(2010)
Wang Zhen,Ge Liangpeng,Rong Xinzhou,Wei Hong,Liu Lizhu,Yang Ronghua,Zhang Tao.Irradiated pigskin graft dressing and recombinant human epidermal growth factor gel application in treatment of small-area partial-thickness burn: report of 135 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(01):71-73.
Wang Zhen,Ge Liangpeng,Rong Xinzhou,Wei Hong,Liu Lizhu,Yang Ronghua,Zhang Tao.Irradiated pigskin graft dressing and recombinant human epidermal growth factor gel application in treatment of small-area partial-thickness burn: report of 135 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(01):71-73.DOI:
Irradiated pigskin graft dressing and recombinant human epidermal growth factor gel application in treatment of small-area partial-thickness burn: report of 135 cases
Objective To investigate the therapeutic effect of the application of recombinant human epidermal growth factor (rhEGF) gel and the dressing of the irradiated pigskin graft in the treatment of small-area partial-thickness burn injury
and compare the outcomes with topically use of povidone iodine. Methods Totally 135 cases of patients with TBSA10% partial-thickness burns admitted in our hospital from March 2007 to March 2008 were randomly divided into 3 groups: rhEGF gel groups (n=53)
irradiated pigskin graft group (n=40) and PVP-I groups (povidone iodine
n=53). The wound healing time
prognosis and results after 1 year’s follow-up. Results With different treatments
the healing time: PVP-I grouprhEGF gel group irradiated pigskin graft group [(14.42±2.10)d vs (9.82±1.52)d vs (8.09±1.05)d]. Irradiated pigskin group and rhEGF gel group had better effect than the control group in the treatment of partial-thickness burn patients
and significantly shorten the average healing time of 3 to 5 d (P0.01). Irradiated pigskin graft group was slightly better than the rhEGF gel group (P0.05)
but the difference was not as significant as with the control group. Irradiated pigskin graft group and rhEGF gel group had good healing effect: lesser pain and doctor’s workload (P0.01) and lesser pigmentation and fewer scars in some patients after 1 year’s follow-up. Conclusion Irradiated pigskin graft and rhEGF have exact effect and sound prognosis in the treatment of partial-thickness burn