CHEN Rong,ZHANG Shao-xiang,YIN Zhi-yong,ZHAO Hui,ZHANG Wei-guo,CHEN Jin-hua.Application of 64-slice multi-detector CT in deceleration brain injury in rabbits after falls[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(21):2020-2023.
CHEN Rong,ZHANG Shao-xiang,YIN Zhi-yong,ZHAO Hui,ZHANG Wei-guo,CHEN Jin-hua.Application of 64-slice multi-detector CT in deceleration brain injury in rabbits after falls[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(21):2020-2023.DOI:
Application of 64-slice multi-detector CT in deceleration brain injury in rabbits after falls
Objective To study the nueroimaging features of deceleration brain injury after falls in rabbits by 64-slice multidetector CT. Methods The deceleration brain injury was produced in rabbits by a self-made impactor setup. Totally 30 rabbits were divided randomly and equally into 3 groups according to the free-falling heights (2.5
3.5
and 7 m respectively)
and another 6 rabbits served as control group. Noncontrast CT scanning (64-slice multi-detector) was performed in 3 to 4 h after trauma
and CT image features of deceleration brain injury of rabbits were compared with macroanatomy
microanatomy and high speed camera records. Results The severity of brain injury of rabbits was increased with fall height. Subarachnoid hemorrhage was the commonest intracranial lesion. Contusion and laceration of brain located at the site of impact and contra-coup (away from the site of impact)
and the latter was more severe. Basal fracture located at the site of contra-coup. Noncontrast CT displayed the shape and location of skull fracture exactly
and was corresponding with the site of impact recording by high speed camera. On CT scan
almost all of brain injuries were revealed in the highest group
some minor brain injury of rabbits in the moderate group were false negative; and all head of rabbits were negative in the lowest group. Conclusion Noncontrast 64-slice multi-detector CT displays the characteristic of severe and partial moderate deceleration brain injury from falls in rabbits. Data obtained by this procedure may provide valuable information for brain injury mechanism.
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Related Author
WU Yue
ZHU Yu
LI Qinghui
LI Tao
刘祥凤1
陈倩
秦志刚
杨子恒
Related Institution
State Key Laboratory of Trauma and Chemical Poisoning, Department of War Trauma, Shock and Blood Transfusion, Daping Hospital, Army Medical University(Third Military Medical University)