Objective    To assessed the image quality and diagnostic value of the coronary artery diseases with 64-slice spiral computed tomography (64-SCT) angiography.     Methods    A retrospective image analysis of 39 patients who were diagnosed with coronary heart disease by both the 64-SCT and the invasive coronary angiography (CAG).     Results    In 507 coronary artery segments (13 coronary segments for each patient)

1-

2-

3-class image quality by 64-SCT were in 185 (36.5%)

236 (46.5%)

86 (16.9%) segments respectively

and the heart rate range was respectively 62±5

66±4 and 75±10 per minute. Totally 421/507 (83.1%) segments that were of 1-

2-class image quality

met the requirements of clinical diagnosis

whereas 86/507 (16.9%) segments could not be sufficiently evaluated because of severe calcifications (51/86

59.3%) and/or motion artifacts (35/86

40.7%). Taking CAG as the gold standard diagnostic technique for coronary heart disease

of the lesions≥50% stenosis by 64-SCT (without any exclusion criteria)

the overall sensitivity

specificity

accuracy

positive predictive value

and negative predictive value were 89.8%

94.9%

93.3%

88.5%

95.5%

respectively.     Conclusion    Our results indicate high diagnostic accuracy of coronary artery disease by 64-SCT compared to CAG. 64-SCT is a simple

convenient

safe and reliable

non-invasive effective method for diagnosis of coronary heart disease.