Clinical application of DWI in diagnosis of glioma and meningioma

张启川; 张冬; 廖翠薇; 舒通胜; 马琼英; 孙清荣; 王文献

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Clinical application of DWI in diagnosis of glioma and meningioma

更新时间：2026-01-09

- Clinical application of DWI in diagnosis of glioma and meningioma
- Journal of Army Medical University Vol. 30, Issue 16, Pages: 1522-1525(2008)
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  CLC： R739.4;R814.3;R816.1
- Published：2008
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张启川,张冬,廖翠薇,舒通胜,马琼英,孙清荣,王文献.弥散加权成像对胶质瘤和脑膜瘤的诊断价值[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1522-1525.

　ZHANG Qi-chuan,ZHANG Dong,LIAO Cui-wei,SHU Tong-sheng,MA Qiong-ying,SUN Qing-rong,WANG Wen-xian.Clinical application of DWI in diagnosis of glioma and meningioma[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(16):1522-1525.
张启川,张冬,廖翠薇,舒通胜,马琼英,孙清荣,王文献.弥散加权成像对胶质瘤和脑膜瘤的诊断价值[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1522-1525. DOI：

　ZHANG Qi-chuan,ZHANG Dong,LIAO Cui-wei,SHU Tong-sheng,MA Qiong-ying,SUN Qing-rong,WANG Wen-xian.Clinical application of DWI in diagnosis of glioma and meningioma[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(16):1522-1525. DOI：

摘要

目的探讨弥散加权成像（diffusionweighted imaging，DWI）及表观弥散系数（apparent diffusion coefficients，ADC）测量对胶质瘤和脑膜瘤的诊断价值。方法对经手术病理证实的17例胶质瘤和20例脑膜瘤患者进行常规MRI序列扫描和DWI检查，对照分析病变的实质部分、周围水肿区以及正常脑组织的ADC值、指数表观弥散系数（eADC)值。结果 17例胶质瘤中10例DWI表现为高信号，4例为稍高信号，3例为等信号。20例脑膜瘤中18例DWI表现为等高信号。脑膜瘤、胶质瘤的ADC值和eADC值均与正常的脑组织有统计学差异(P0.01)，Ⅲ、Ⅳ级胶质瘤实质部分的ADC值及其瘤周水肿区的ADC值明显低于Ⅰ、Ⅱ级胶质瘤(P0.05)。结论 ADC值难以对胶质瘤和脑膜瘤做出定性诊断

但DWI和ADC值可用于对脑肿瘤的评价，结合两者可提供肿瘤内部功能信息。

Abstract

Objective To explore the clinical value of diffusion weighted imaging (DWI) and apparent diffusion coefficients (ADC) measurement in the diagnosis of glioma and meningioma. Methods Seventeen patients with gliomas and twenty patients with meningioma underwent routine MRI scan and DWI. Comparisons of apparent diffusion coefficients (ADC)and exponential diffusion coefficients (eADC) were made among tumor parenchymas

peripheral edema regions and normal tissues. Results Of 17 cases of gliomas

tumor parenchymas of 10

3 cases exhibited hyper

iso

hypo-intensity on DWI respectively. Of 20 cases of meningioma

18 cases showed iso- and hyper-intensity on DWI. The results from ADC or eADC showed significant statistical difference between glioma

meningioma and normal brain tissue (P0.01); The results of grade Ⅰ-Ⅱ glioma were also statistically different with those of and grade Ⅲ-Ⅳ glioma and meningioma (P0.05). In peripheral edema regions

the results from ADC (eADC) of grade Ⅰ-Ⅱ glioma were significantly lower than those of grade Ⅲ-Ⅳ glioma and meningoma (P0.05). Conclusion DWI and ADC may evaluate brain tumors by providing the internal functional information

though ADC itself can not be used to differentiate brain tumors.

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Department of Pathology， Frist Affiliated Hospital， Army Medical University （Third Military Medical University）

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