Zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain

任庆兰; 吴永忠; 陈晓品; 戴晓波

您当前的位置：

首页 >

文章列表页 >

Zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain

更新时间：2026-01-09

- Zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain
- Journal of Army Medical University Vol. 30, Issue 2, Pages: 176-178(2008)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R730.53;R730.55;R738.1
- Published：2008
- 稿件说明：
移动端阅览
任庆兰,吴永忠,陈晓品,戴晓波.唑来膦酸联合单次或多次分割放射治疗转移性骨痛的临床分析[J].陆军军医大学学报(原第三军医大学学报),2008,30(02):176-178.

　REN Qing-lan,WU Yong-zhong,CHEN Xiao-pin,DAI Xiao-bo.Zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(02):176-178.
任庆兰,吴永忠,陈晓品,戴晓波.唑来膦酸联合单次或多次分割放射治疗转移性骨痛的临床分析[J].陆军军医大学学报(原第三军医大学学报),2008,30(02):176-178. DOI：

　REN Qing-lan,WU Yong-zhong,CHEN Xiao-pin,DAI Xiao-bo.Zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(02):176-178. DOI：

摘要

目的观察唑来膦酸联合单次或多次分割放射治疗转移性骨痛的疗效和毒副反应。方法 98例骨转移患者分A和B两组。A组为唑来膦酸联合单次分割（8 Gy/1F）照射组，共48例。B组为唑来膦酸联合多次分割(30 Gy/10 F)照射组，共50例。结果 A组和B组疼痛缓解率分别为91.7%和92.0%，活动能力改善总有效率为89.6%和90.0%，毒副反应率相似，两组间比较无统计学差异（P0.05）。结论唑来膦酸联合单次与多次分割放射治疗转移性骨痛的疗效相似。推荐临床采用唑来膦酸联合单次分割放射治疗转移性骨痛，其安全、有效、经济、方便。

Abstract

Objective To observe the effects and toxicity of zoledronic acid combined with single or multiple fraction radiotherapy for metastatic bone pain. Methods Ninety-eight patients suffering from metastatic bone pain were randomized into group A (n=48) receiving zoledronic acid and single fraction radiotherapy

and group B (n=50) receiving zoledronic acid and multiple fraction radiotherapy. Results The effective rate in group A and group B was 91.7% and 92.0%

and their improvement of activities was 89.6% and 90%

respectively. The ratio of adverse reactions in two groups were similar

with no statistical difference (P0.05). Conclusion Zoledronic acid combined with single or multiple fraction radiotherapy has similar clinical response. Zoledronic acid combined with single fraction is an efficient and cost-effective alternative to traditional multiple fraction radiotherapy for metastatic bone pain.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Current status of pain and its influencing factors in patients with chronic wounds: a cross-sectional survey

Influencing factors of pain during ultrasound-guided puncture sclerotherapy for ovarian endometriotic cysts via transabdominal and transvaginal approaches

Comparison of angiogenetic effects of different dose fractionated radiotherapy on rectal cancer cells

Predictive value of peripheral blood neutrophil to lymphocyte ratio in radiotherapeutic efficacy for NSCLC patients

Healthcare seeking behavior of pain along with its related factors at outpatient department in a hospital in Chongqing: a cross-sectional survey

Related Author

WANG Lihua

LI Haisheng

LI Maojun

LI Ning

FU Congying

XIE Rongkai

XIONG Xi

WANG Qin

Related Institution

School of Nursing， Guizhou University of Traditional Chinese Medicine

State Key Laboratory of Trauma and Chemical Poisoning， Institute of Burn Research

Hospital Administration Office， First Affiliated Hospital， Army Medical University （Third Military Medical University）

Department of Obstetrics and Gynecology， Second Affiliated Hospital， Army Medical University （Third Military Medical University）

Department of Oncology, the First Affiliated Hospital of Chongqing Medical University

⁰