Differential diagnosis of diffuse glomerular nodular changes

李敛; 余荣杰; 赵洪雯; 吴雄飞

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Differential diagnosis of diffuse glomerular nodular changes

更新时间：2026-01-09

- Differential diagnosis of diffuse glomerular nodular changes
- Journal of Army Medical University Vol. 30, Issue 2, Pages: 107-109(2008)
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  CLC： R446.8;R447;R692
- Published：2008
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李敛,余荣杰,赵洪雯,吴雄飞.具有肾小球弥漫结节样改变的肾脏病理诊断[J].陆军军医大学学报(原第三军医大学学报),2008,30(02):107-109.

　LI Lian,YU Rong-jie,ZHAO Hong-wen,WU Xiong-fei.Differential diagnosis of diffuse glomerular nodular changes[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(02):107-109.
李敛,余荣杰,赵洪雯,吴雄飞.具有肾小球弥漫结节样改变的肾脏病理诊断[J].陆军军医大学学报(原第三军医大学学报),2008,30(02):107-109. DOI：

　LI Lian,YU Rong-jie,ZHAO Hong-wen,WU Xiong-fei.Differential diagnosis of diffuse glomerular nodular changes[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(02):107-109. DOI：

摘要

目的探讨肾小球弥漫结节样改变的病理学诊断特征。方法回顾性总结分析127例肾小球以弥漫结节样改变为主的肾活检患者的病理诊断。结果肾小球弥漫结节样改变在糖尿病肾病、淀粉样变性肾损害、膜增生性肾炎、Ⅳ型狼疮性肾炎中最为常见，还可见于轻链沉积病、冷球蛋白血症肾损害等少见疾病中。结论肾小球弥漫结节样改变可有多种不同的肾脏病理诊断，我们应结合临床和实验室数据进行相应的鉴别诊断。

Abstract

Objective To explore the clinical and pathological characteristics in diagnosing the renal diseases with diffuse glomerular nodular changes. Methods The clinical and pathological data of 127 patients whose renal pathological feature was mainly diffuse glomerular nodular changes were retrospectively analyzed. Results The most common diagnosis was diabetic nephropathy and renal amyloidosis

and sometimes light chain deposit diseases and Mix cryoglobulinemia. Conclusion Diffuse glomerular nodular changes occurred in many diseases. We should make differential diagnosis based on the clinical symptoms

the results of laboratory examinations and the renal pathological characteristics.

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