LUO Rong,HUANG Ying,LIU Lan,CHEN Yuan,YANG Yong-hong.Clinical features and drug resistance of Moraxella Catarrhalis in children with lower respiratory infections in Chongqing[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(18):1818-1820.
LUO Rong,HUANG Ying,LIU Lan,CHEN Yuan,YANG Yong-hong.Clinical features and drug resistance of Moraxella Catarrhalis in children with lower respiratory infections in Chongqing[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(18):1818-1820.DOI:
Clinical features and drug resistance of Moraxella Catarrhalis in children with lower respiratory infections in Chongqing
drug resistance and prognosis of moraxella catarrhalis infection in order to guide the rational administration. Methods Sputum from 10 442 children with lower respiratory infection in our hospital were cultured. Susceptibility test and beta-lactamase were carried out to isolated moraxella catarrhalis. Then clinical features and prognosis of the infection were analyzed. Other respiratory pathogens were detected. Results Moraxella catarrhalis infection were popular in infants
frequently accompanied with other pathogens
and the germ was commonly isolated in winter. Its beta-lactamase positive rate was 63.4%. And its drug resistance rate to ampicillin and sulfamethoxazole
were 46.2% and 43.4% respectively
and to oxef and enzyme inhibitor containing antibiotics were less than 5.0%. Conclusion The infection of moraxella catarrhalis in children with respiratory infection is closely related with season and age. Its beta-lactamase positive rate is low. The rate of drug resistance to ampicillin is high. It is necessary for us to monitoring drug resistance and beta-lactamase positive rate of moraxella catarrhalis to guide the rational administration.
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