Objective    To explore the effect of sphincter of Oddi (SO) stenosis on myoelectric activities in dogs.     Methods    After fasted for 16-18 h

the adult mongrel dogs were anesthetized and mechanically damaged by surgery to make stenosis of sphincter of Oddi. Sphincter of Oddi electromyography (SOE) was used to detect electrophysiology at postoperative 4th week when the dogs were under general anesthesia. Then

the SO was resected for pathologic analysis.      Results    In the dogs of SO stenosis

liver function such as TBIL

direct bilirubin was higher and the diameter of CBD by ultrasonograph was larger than preoperative ones. The fibrosis of SO was observed pathologically. However

in the control dogs

no obvious changes were found in liver function

CBD diameter as well as SO status. The voltage amplitude of slow waves and spikes in the experimental dogs decreased compared with control ones.     Conclusion    The model of SO stenosis was established successfully. SO stenosis caused significant electrophysiologic changes.