Effect of taurine on serum glucose and expression of GLUT2, GLUT5 in intestinal tissue of rats exposed to hypobaric hypoxia

白雪; 糜漫天; 陈芳

您当前的位置：

首页 >

文章列表页 >

Effect of taurine on serum glucose and expression of GLUT2, GLUT5 in intestinal tissue of rats exposed to hypobaric hypoxia

更新时间：2026-01-09

- Effect of taurine on serum glucose and expression of GLUT2, GLUT5 in intestinal tissue of rats exposed to hypobaric hypoxia
- Journal of Army Medical University Vol. 29, Issue 20, Pages: 1947-1950(2007)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  CLC： R151.2;R339.54;R977.4
- Published：2007
- 稿件说明：
移动端阅览
白雪,糜漫天,陈芳.牛磺酸对高原低氧大鼠血清葡萄糖水平及小肠组织GLUT2、GLUT5 mRNA表达的影响[J].陆军军医大学学报(原第三军医大学学报),2007,29(20):1947-1950.

　BAI Xue,MI Man-tian,CHEN Fang.Effect of taurine on serum glucose and expression of GLUT2, GLUT5 in intestinal tissue of rats exposed to hypobaric hypoxia[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(20):1947-1950.
白雪,糜漫天,陈芳.牛磺酸对高原低氧大鼠血清葡萄糖水平及小肠组织GLUT2、GLUT5 mRNA表达的影响[J].陆军军医大学学报(原第三军医大学学报),2007,29(20):1947-1950. DOI：

　BAI Xue,MI Man-tian,CHEN Fang.Effect of taurine on serum glucose and expression of GLUT2, GLUT5 in intestinal tissue of rats exposed to hypobaric hypoxia[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(20):1947-1950. DOI：

摘要

目的观察牛磺酸对高原低氧大鼠血清葡萄糖水平及小肠组织GLUT2、GLUT5 mRNA表达的影响。方法动物经基础饲料或添加牛磺酸饲料喂养7 d后，利用低压舱分别模拟4 500、5 500 m海拔高度高原低氧，分别在高原低氧处理后第2、6、12、24、48、72小时处死动物，同时设平原对照组，测定血清葡萄糖水平，并剪取小肠组织，RT-PCR检测 GLUT2、GLUT5 mRNA表达。结果低氧条件下大鼠血清葡萄糖水平明显下降，小肠组织中GLUT2、GLUT5的表达显著降低，但添加牛磺酸组血清葡萄糖水平及小肠组织中GLUT2、GLUT5的表达均明显高于相应对照组。结论牛磺酸能够显著提高高原低氧大鼠血清葡萄糖水平及小肠组织中GLUT2、GLUT5的表达。

Abstract

Objective To observe the effect of taurine on serum glucose and expression of GLUT2

GLUT5 in the intestinal tissue of rats exposed to hypobaric hypoxia. Methods After 7-day nutritional intervention with taurine

rats were exposed to 4 500-meter and 5 500-meter high altitude in a hypobaric chamber respectively. The level of serum glucose and the expressions of GLUT2

GLUT5 in the intestinal tissue were determined at 2nd

6th

12th

24th

48th

72th h after taurine intervention. Results After exposure to hypobaric hypoxia

the serum glucose and the expressions of GLUT2

GLUT5 in intestinal tissue decreased significantly. However

they were higher in taurine intervention groups at each phase point than that in control groups. Conclusion The taurine intervention can increase the serum glucose and the expressions of GLUT2

GLUT5 in the intestinal tissue of rats after exposure to hypobaric hypoxia.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Role of urotensin Ⅱ and intermedin in taurine alleviating oleic acid-induced acute lung injury in rats

Effects of taurine on p38 mitogen-activated protein kinase signaling pathway in Kupffer cells from severe acute pancreatitis rats

Protective mechanisms of IRAK-4 inhibited by taurine preconditioning in liver graft ischemia/reperfusion injury in rats

Protective effects of taurine on inner plexiform layer of retina in rats exposed to hypobaric hypoxia

Protective effects of taurine against retinal damage in diabetic rats

Related Author

郑涛

于忠和

宋斌

黄庆勇

孙科

欧志兵

陈蓁臻

龚建平

Related Institution

No data

⁰