Objective    To report the limb salvage surgery for lower extremity with major blood vessels invaded by tumors.     Methods    Two patients

with major vessels of extremity were invaded by tumor

were included. Case one

male

40 years old

a ball-like mass about 102 cm×72 cm×45 cm on the left leg

occupying from the inferior abdomen to the knee

which was diagnosed as sarcoenchondroma. Case two

female

63 years old

a mass about 50 cm×30 cm×26 cm on the left leg

from the left inferior abdomen to the knee

diagnosed as liposarcoma. Before operation

Doppler ultrasonography and CT examination or MRI scanning were used to indicate the relationship of tumor and vessels. After the tumor was removed

the arterial reconstructions were performed by using great saphenous vein allograft.     Results    After surgical treatment

the blood circulation and nervous function of the left legs of the two patients were basically normal. The two patients were followed up for 12 or 22 months respectively

and no tumor recurrence.     Conclusion    The surgical treatment for patients with malignant tumor affecting arteries is complicated. For some patients with major vessels invaded by tumor

the combination of tumor removal and major blood vessels reconstruction is a practical method.