Expression of tumor suppressor PTEN protein in central nervous system of adult rats

蔡其燕; 姚忠祥

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Expression of tumor suppressor PTEN protein in central nervous system of adult rats

更新时间：2026-01-09

- Expression of tumor suppressor PTEN protein in central nervous system of adult rats
- Journal of Army Medical University Vol. 29, Issue 5, Pages: 384-386(2007)
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  CLC： R322.81;R329.24;R341
- Published：2007
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蔡其燕,姚忠祥.肿瘤抑制因子PTEN蛋白在成年大鼠中枢神经系统的表达[J].陆军军医大学学报(原第三军医大学学报),2007,29(05):384-386.

　CAI Qi-yan,YAO Zhong-xiang.Expression of tumor suppressor PTEN protein in central nervous system of adult rats[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(05):384-386.
蔡其燕,姚忠祥.肿瘤抑制因子PTEN蛋白在成年大鼠中枢神经系统的表达[J].陆军军医大学学报(原第三军医大学学报),2007,29(05):384-386. DOI：

　CAI Qi-yan,YAO Zhong-xiang.Expression of tumor suppressor PTEN protein in central nervous system of adult rats[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(05):384-386. DOI：

摘要

目的观察PTEN在成年大鼠中枢神经系统（central nervous system

CNS）的表达情况。方法用免疫组织化学ABC法显示大鼠CNS中PTEN阳性免疫反应产物。结果 PTEN阳性反应产物广泛分布于大鼠的CNS内，阳性细胞的分布主要表现为较多、中等量和少量3种情况，其亚细胞定位包括细胞质、细胞核和细胞质突起。结论明确PTEN在成年大鼠CNS中的表达模式。

Abstract

Objective To investigate the expression characteristics of the phosphatase and tensin homolog deleted on the chromosome 10 (PTEN) in the central nervous system(CNS) of adult rats. Methods Immunohistochemical staining was used to demonstrate the PTEN-like positive immunohistochemical product. Results Expression of PTEN was extensive in the CNS. The distribution of positive cells was strong

moderate or weak and its subcellular localization included the cytoplasm

nuclei and processes. Conclusion The present results identify the expression of PTEN protein in the CNS of adult rats.

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