Effect of GlcNAc against activation of bacterial cryptic growth cells  to mast cells

刘俊康; 吴小兰; 陈杰; 徐启旺

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Effect of GlcNAc against activation of bacterial cryptic growth cells to mast cells

更新时间：2026-01-09

- Effect of GlcNAc against activation of bacterial cryptic growth cells to mast cells
- Journal of Army Medical University Vol. 29, Issue 7, Pages: 579-581(2007)
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  CLC： R378.2;R574.02;R977.6
- Published：2007
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刘俊康,吴小兰,陈杰,徐启旺.缓激常泰拮抗细菌潜生体对肥大细胞激活作用的实验研究[J].陆军军医大学学报(原第三军医大学学报),2007,29(07):579-581.

　LIU Jun-kang,WU Xiao-lan,CHEN Jie,XU Qi-wang.Effect of GlcNAc against activation of bacterial cryptic growth cells to mast cells[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(07):579-581.
刘俊康,吴小兰,陈杰,徐启旺.缓激常泰拮抗细菌潜生体对肥大细胞激活作用的实验研究[J].陆军军医大学学报(原第三军医大学学报),2007,29(07):579-581. DOI：

　LIU Jun-kang,WU Xiao-lan,CHEN Jie,XU Qi-wang.Effect of GlcNAc against activation of bacterial cryptic growth cells to mast cells[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(07):579-581. DOI：

摘要

目的观测缓激常泰拮抗细菌潜生体激活肥大细胞的作用。方法以头孢呋辛钠诱导大肠杆菌产生

体外以细菌潜生体为对照，分别观测不同剂量缓激常泰对细菌潜生体激活肥大细胞的拮抗作用。结果中、高剂量的缓激常泰具有显著的拮抗作用，与对照组有显著性差异。结论一定剂量的缓激常泰具有稳定肥大细胞的作用。

Abstract

Objective To demonstrate the inhibitory effect of GlcNAc on the bacterial cryptic growth cells (CGC) activating mast cells. Methods E.coli. CGC was induced by Zinacef

in vitro taking the CGC acting on mast cells as control. The antagonistic effect of GlcNAc on mast cells activated by CGC with different dosages was demonstrated. Results The significant inhibitory effect of GlcNAc against the activation of CGC on mast cells was found as compared with controls. Conclusion Certain dosage of GlcNAc possesses the capacity of stabilizing mast cells. This has laid a foundation for elucidating the therapeutic effect of GlcNAc on irritable bowel syndrome.

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