Objective     To discuss the bladder-preserving strategy for bladder tumor.      Methods     Totally 249 cases of bladder tumor were studied retrospectively. The analysis of overall recurrence rate

survival rate and the first recurrence-free duration according to operative methods

drugs for therapeutic bladder perfusion

and clinical stages was carried out.      Results     The first recurrence-free duration was not influenced by operative methods and perfusion drugs significantly. Although the overall recurrence rate and short-term survival rate were not influenced by operative methods

but the hi

ghest 10-year survival rate (77.3%) occurred in the patients received transurethral resection of bladder tumor (TURB). The recurrence rate

3-year

5-year and 10-year survival rate of the patients applied to different perfusion drug were statistically different

with the lowest recurrence rate (28.2%) in patients applied Bacillus Calmette-Guerin (BCG) and the highest survival rate was in patients applied BCG (3-year: 100%

10-year: 81.7%). According to clinical stage

the survival rate was of no statistical difference among patients belonging to T

is

T

a

T

1

stages

and of significant difference between T

2-4

and the other three stages. The overall recurrence rate were not significantly different among T

is

T

a

and T

2-4

stages.      Conclusion     TURB combined with BCG perfusion produces favorable prognosis for bladder tumor patients without muscle-involved

while bladder-preserving operation is not beneficial for patients with muscle-involved bladder tumor.