青岛大学附属医院内分泌与代谢性疾病科,青岛 266000
Received:13 October 2025,
Revised:2025-11-19,
Accepted:03 December 2025,
Published:27 October 2026
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Liu Mengting,Sun Xiaofang.Research advances in fatty liver disease associated with growth hormone deficiency-related metabolic dysfunction[J].Journal of Chongqing Medical University,
Liu Mengting,Sun Xiaofang.Research advances in fatty liver disease associated with growth hormone deficiency-related metabolic dysfunction[J].Journal of Chongqing Medical University, DOI:10.13406/j.cnki.cyxb..
生长激素(growth hormone,GH)在人体的生长发育过程中发挥着至关重要的作用,同时,它在脂肪代谢调节中也起着重要的作用。近年来,越来越多的临床研究成果表明,代谢功能障碍相关脂肪性肝病(metabolic dysfunction-associated fatty liver disease,MASLD)与生长激素缺乏症(growth hormone deficiency,GHD)之间存在着密切的联系,但具体机制尚不明确。因此,本文旨在探讨GHD在MASLD发病过程中的病理生理机制,为GHD相关MASLD的治疗提供更多理论依据。
Growth hormone plays a crucial role in human growth and development,and it also plays an important role in regulating fat metabolism. In recent years,an increasing number of clinical reports and research findings have shown that metabolic dysfunction-associated steatotic liver disease(MASLD) is closely associated with growth hormone deficiency(GHD),but the specific mechanism remains unclear. Therefore,this article mainly focuses on the pathophysiological mechanism of GHD in the development of MASLD,so as to provide a theoretical basis for the treatment of GHD-related MASLD.
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